- "The gonad elaborates through its internal secretions the chemical products which are taken up by the circulation and carried to the central nervous system, and there erotization results. That these substances of internal secretion have a selective action seems probable, and that such substances are stored in the central nervous system, seems, in view of recent experiments, quite certain... O'Malleey thinks that the direct action of the chemical products of the gonads through the nervous system influences the growth and increased metabolism of every tissue of the body. That there is a direct relationship between the gonads and the hypophysis is fairly well established... Since the time of Hippocrates and Aristotle, it has been believed that there was a coordination between the testicular fluid and the nervous system, brain and cord."
Footnotes:
1. Max Thorek, The Human Testis and its Diseases. (1924)